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Brand Names:

Contraindications:

Uses:

• This medicine, like all medicines used to treat cancer, is very strong. Make sure you understand why you are getting it and what the risks and benefits of treatment are. It is important for you to work closely with your doctor.
• Your doctor will prescribe your exact dose and tell you how often it should be given.
• Your medicine will be given through a tube put in one of your veins, usually in your arm, wrist, or hand and sometimes in your chest. This is called intravenous (in-tra-VEEN-us), or IV.
• Your medicine will be given by a nurse or other caregiver trained to give cancer drugs.
• Do not get the medicine on your skin. If this happens rinse your skin well with warm water. If the medicine gets in your eyes, rinse your eyes with large amounts of water, and tell your caregiver.

• This medicine needs to be given on a regular schedule. If you miss a dose, call your doctor, home health caregiver, or the clinic where you have your treatments for instructions.

Storage:

• If you have your treatments at a clinic, the staff at the clinic will keep your medicine there.
• If you have your treatments at home, you may need to store your medicine.
• Keep the medicine away from heat and light. Ask your caregiver if you should store the medicine in the refrigerator or at room temperature and how long you can keep the medicine before it must be used.
• Keep all medicine out of the reach of children.
• If you have your treatments at home, you should be given a special container for the used needles, medicine bag or bottles, and tubes. Put it where children or pets cannot reach it.

Special precautions:

• Some medicines may become harmful when taken with mitoxantrone. Make sure your doctor knows what medicines you take.
• You should not use aspirin or any product that has aspirin it (such as some cold medicines) unless you have talked to your doctor.
• Talk to your doctor before getting any vaccines (such as flu shots).

Warnings:

• Do not breastfeed while you are being given this medicine.
• If you start to have pain, redness, or swelling on the area of your skin where the IV is given, tell your nurse or caregiver right away.
• You may get infections more easily while getting this medicine. Stay away from crowds or people with colds, flu, or other infections.
• This medicine may turn urine a bluish-green color. This is normal. You may want to protect your clothing from being stained. The whites of your eyes may also be turned a bluish color.
• Mitoxantrone can cause nausea and vomiting. Your doctor may prescribe medicine to keep you from feeling sick and throwing up. If the medicine does not help (you can't keep liquids down), call your doctor.
• Do not get pregnant while you or your sexual partner are receiving mitoxantrone. Use an effective method of birth control while you are being treated with this medicine.
• If you are pregnant, talk to your doctor before you start your treatments.

Side Effects:

• Fever, chills, or sore throat
• Unusual bleeding or bruising
• Painful mouth sores that keep you from drinking liquids
• Uncontrollable nausea, vomiting, or diarrhea
• Trouble breathing, swelling of feet and ankles
• Hives, rash, or severe itching
• Pain, redness, or swelling where the IV is given
• Loss of appetite
• Hair loss