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Brand Names:

Contraindications:

Uses:

• This medicine, like all medicines used to treat cancer, is very strong. Make sure you understand why you are getting it and what the risks and benefits of treatment are. It is important for you to work closely with your doctor.
• You will receive this medicine while you are in a hospital or chemotherapy treatment center. A nurse or other caregiver trained to give cancer drugs will give your treatment.
• Your medicine will be given through a tube that is put in a vein, usually in your arm, wrist, or hand and sometimes in your chest. This is called intravenous (in-tra-VEEN-us), or IV.
• The medicine is usually given once every 21 to 28 days.
• You may also receive other medicines to help prevent nausea and vomiting.
• Do not get the medicine on your skin. If it does, wash the area well with soap and water, and tell your caregiver.
• Keep all medicine away from children.

• This medicine needs to be given on a regular schedule. If you miss a dose, call your doctor, home health caregiver, or clinic where you get your treatments for instructions.

Storage:

• If you have your treatments at a clinic, the staff at the clinic will keep your medicine there.
• If you have your treatments at home, you may need to store your medicine. Keep the medicine in the carton until you are ready to use it. Keep the powder at room temperature, away from heat, moisture, and direct light. Keep the liquid in the refrigerator. Do not freeze.
• If you have your treatments at home, you should be given a special container for the used needles, medicine bag or bottles, and tubes. Put it where children or pets cannot reach it.

Special precautions:

• Some medicines may become harmful when taken with doxorubicin. You should not use any other medicines without asking your doctor.
• You should not use aspirin or any product that has aspirin in it (such as some cold medicines) unless you have talked to your doctor.
• Avoid drinking alcohol.
• Talk to your doctor before getting any vaccines (such as flu shots).

Warnings:

• Do not breastfeed while you are getting this medicine.
• If you start to have pain, redness, or swelling where the IV is given tell your caregiver right away.
• This medicine may turn your urine red for 1 or 2 days after your treatment. This is normal. You may need to protect your clothing from being stained.
• You may get infections more easily while being treated with this medicine. Stay away from crowds or people with colds, flu, or other infections.
• Tell your doctor if you have liver or heart disease before you get this medicine.
• Your doctor may want to test your heart while you are receiving treatments with doxorubicin and after treatments have stopped. Be sure to keep all appointments.
• This medicine may make your mouth sore and irritated. Brush your teeth with a soft-bristle toothbrush or mouth swab.
• Chemotherapy causes nausea and/or vomiting in most people, sometimes even after receiving medicines to prevent it. Ask your doctor or nurse about other ways to control these side effects.
• Do not get pregnant while you or your sexual partner are receiving doxorubicin. Use two forms of birth control while you are being treated with this medicine. This is very important whether you are a man or a woman.
• If you are pregnant, talk to your doctor before you start your treatments.

Side Effects:

• Blood in urine or stools
• Difficulty swallowing, pain or burning in throat or chest
• Fever, chills, or sore throat
• Hives, rash, or severe itching
• Redness, swelling, or pain where the IV is given
• Sores, ulcers, or white spots on lips, mouth, or tongue
• Trouble breathing, swelling in legs and feet
• Uncontrollable nausea, vomiting, or diarrhea
• Unusual bleeding or bruising
• Loss of appetite
• Hair loss