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Dihydroergotamine (Injection)
Treats migraine headaches. Belongs to a class of drugs called ergot alkaloids
Brand Names:
D.H.E. 45
Contraindications:
You should not use this medicine if you have had an allergic reaction to dihydroergotamine or related medicines that contain ergotamine or ergot. You should not use it if you are pregnant or breastfeeding, or if you have heart or circulation problems, chest pain (angina), a blood infection, severe high blood pressure, or kidney or liver disease
Uses:
Injectable
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Your doctor will tell you how much medicine to use and how often.
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You may be told to use the medicine at the first sign of a migraine headache.
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An IM injection is a shot given in your muscle (upper arm, thigh, buttocks).
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A doctor, nurse, or other health caregiver will teach you how to give yourself the shots. You may want a family member or friend to also learn how to give your medicine.
If a dose is missed:
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Dihydroergotamine is used when you have a migraine. It is not used on a regular schedule.
Storage:
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Store the medicine at room temperature, away from heat and direct light.
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Before each injection, look carefully at the medicine, if you see any solid pieces or if the medicine has changed color, You should not use that medicine. Get a new vial of medicine.
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If you have your treatments at home, you should be given a special container for the used needles. Keep it where children and pets cannot reach it.
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Keep all medicine out of the reach of children.
Special precautions:
Before taking, tell your doctor and pharmacist if you are allergic to any medications. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. tell your doctor if you have or have ever had heart failure or liver disease. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking, call your doctor
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Talk to your doctor before using this medicine if you are using decongestants (such as pseudoephedrine or phenylpropanolamine), midodrine, diet pills, or if you use other medicine to treat migraines (such as sumatriptan (Imitrex®) or zolmitriptan (Zomig®).
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Make sure your doctor knows if you are using propranolol (Inderal®), medicine for your heart, or antibiotics for an infection (such as erythromycin or clarithromycin).
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It is best not to smoke tobacco while using this medicine. Smoking may increase side effects of the medicine.
Warnings:
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You should not use more of this medicine that your doctor ordered.
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This medicine helps stop migraine headaches. It does not relieve pain or stop other kinds of headaches.
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Do not get pregnant while you are being treated with this medicine. Dihydroergotamine may cause birth defects or be harmful to an unborn baby.
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This medicine may make you dizzy or drowsy. Avoid driving or using machinery until you know how the medicine will affect you.
Side Effects:
Tell your doctor if any of these symptoms are severe or do not go away:
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Coldness, numbness, tingling, or a blue color in your fingers and toes
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Hives, rash, severe itching
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Muscle pain in your arms and legs
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Weakness in your legs
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Chest pain
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Fast, slow, or irregular heartbeat
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Wheezing or trouble breathing
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Swelling in your face, hands, legs, or feet
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Mild nausea and vomiting
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Mild itching
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Flushing, sweating
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Feeling dizzy or drowsy
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