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Brand Names:

Contraindications:

Uses:

• This medicine, like all medicines used to treat cancer, is very strong. Make sure you understand why you are getting it and what the risks and benefits of treatment are. It is important for you to work closely with your doctor.
• You will receive this medicine while you are in a hospital or chemotherapy treatment center.
• Your medicine will be given through a tube put into your chest. This is called a central venous catheter.
• Before receiving busulfan, you will be given medicines to help prevent vomiting and other side effects.

Special precautions:

• Make sure your doctor knows about all other medicines you are taking or have taken within the week before you receive busulfan.

Warnings:

• If you are pregnant or breastfeeding, talk to your doctor before receiving this medicine.
• Before receiving busulfan, let your doctor know if you have ever had seizures or a head injury.
• Let your doctor know if you have ever received radiation treatments, other stem cell transplants, or other types of chemotherapy.
• Your doctor will need to check your blood at regular times during your treatment.
• Busulfan lowers your body's ability to fight infection. While you are receiving this medicine, avoid exposure to people with colds or infections.
• This medicine causes nausea and vomiting in most people, even after receiving medicines to prevent it. Ask your doctor or nurse about other ways to control these side effects.
• Receiving busulfan may increase your risk of developing other types of cancer or a recurrence of leukemia. Talk to your doctor about this risk.

Side Effects:

• Back pain
• Diarrhea
• Fever, chills, or sore throat
• Sores or ulcers on the lips or in the mouth
• Anxious feeling
• Change in menstrual periods
• Headache
• Loss of appetite
• Skin rash
• Stomach pain
• Trouble sleeping