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Antihemophilic Factor (Injection)
Also called AHF or factor VIII. Prevents and controls bleeding in patients with hemophilia A, a disorder in which blood does not form clots normally
Brand Names:
Alphanate, Koate-DVI, Hemofil-M, Monarc-M, Monoclate-P, Refacto, Recombinate, Kogenate FS, Helixate FS, Hyate:C, Advate
Contraindications:
You should not use this medicine if you have ever had an allergic reaction to antihemophilic factor (AHF)
Uses:
Injectable
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This medicine is given through a tube that goes directly into a blood vein (intravenous, or IV).
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Before receiving AHF, you should be trained to prepare the medicine for injection and know how to use the IV equipment.
If a dose is missed:
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Try not to miss a dose. If possible, have other family members trained to give your treatment in case you cannot give it to yourself.
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If you do miss a dose, ask your doctor or home health caregiver for instructions.
Storage:
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Some brands of AHF are kept in the refrigerator and others can be kept at room temperature.
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Follow the instructions from your home health caregiver for storing your medicine.
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Keep all medicine out of the reach of children.
Special precautions:
Before taking, tell your doctor and pharmacist if you are allergic to any medications. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. tell your doctor if you have or have ever had heart failure or liver disease. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking, call your doctor
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Patients who have hemophilia should not take aspirin, because it may increase bleeding.
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Do not mix any other medicine with the AHF solution, unless directed by your doctor.
Warnings:
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Check with your doctor before taking if you have kidney disease or if you are pregnant or breastfeeding.
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AHF may be taken from donated human blood that has been tested for viruses and treated to keep from spreading infections. The risk of getting HIV (human immunodeficiency virus, the virus that causes AIDS) or hepatitis from this medicine is very low, but cannot be completely eliminated. As a precaution, you should receive a hepatitis B vaccine. AHF products are also available that are not taken from human blood.
Side Effects:
Tell your doctor if any of these symptoms are severe or do not go away:
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Wheezing, trouble breathing, or chest tightness
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Hives or itching
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Swelling of the face, around eyes, or mouth
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Nausea and vomiting
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Yellowing of skin or eyes
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Dark-colored urine
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Fever or chills
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Headache
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Back pain
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Pain where the injection is given
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Tiredness
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