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Brand Names:

Contraindications:

Uses:

• Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles or through a needle placed in one of your veins.
• A nurse or other trained health professional will give you this medicine.
• This medicine is usually given once a week for 12 weeks.
• You may not see improvement in your skin right away. However, your psoriasis may continue to get better even after you have stopped using this medicine.
• After you finish your 12 weeks of treatment, you must wait at least another 12 weeks before you can receive more medicine. Some people may not need more medicine after the first 12-week treatment. If you have questions, talk with your doctor.

• Call your doctor, pharmacist, or treatment clinic for instructions.

Special precautions:

• Make sure your doctor knows if you are also using other medicines that weaken the immune system (such as steroids, chemotherapy, or radiation). Make sure your doctor knows if you are also receiving phototherapy (light or laser therapy) for your psoriasis.
• Talk to your doctor before getting flu shots or other vaccines while you are receiving alefacept. Vaccines may not work as well while you are using this medicine.

Warnings:

• Make sure your doctor knows if you are pregnant or breastfeeding, or if you have HIV or AIDS.
• This medicine lowers the number of certain kinds of blood cells in your body. This means you may get infections more easily. Tell your doctor if you have any kind of infection before you start using this medicine. Also tell your doctor if you have ever had an infection that would not go away or an infection that kept coming back. Call your doctor if you think you have an infection while using this medicine.
• A small number of people who have used this medicine have developed cancer. This is rare. Make sure your doctor knows if you have had cancer before. Talk about this risk with your doctor.
• Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments.
• For women: Tell your doctor if you become pregnant while using this medicine or within 8 weeks after you stop using this medicine.

Side Effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
• Fever
• Muscle pain, headache, chills, and sinus (face and forehead) pain
• Chills
• Dizziness
• Nausea
• Pain, swelling, hardness, or mild bleeding where the shot was given
• Sore throat, cough